%A Michael H. Depledge %T Sea Change: Implications for human health and well-being. %X Climate change is now widely recognised as being one of the greatest threats to human health and well-being in the Mediterranean region in the coming decades. Impacts are being superimposed on those associated with point source and diffuse pollution, habitat and biodiversity loss, overfishing and the development of coastal regions for tourism and industrial activity. This is happening at a time when demographic studies are revealing increased population densities in coastal areas, and indeed, growth in the population of the whole region. In this paper, these issues are reviewed and examined in some detail. The options available to environmental managers and policy makers are discussed. In particular, a shift away from chemical monitoring to biological effects studies is advocated, as is the need for a more integrated approach to policy formulation and implementation. %C Cardiff, Wales %D 2007 %L coastnet965